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P E Clayton Selected Research

Miller-McKusick-Malvaux-Syndrome (3M Syndrome)

1/20133-M syndrome: a growth disorder associated with IGF2 silencing.
12/2012Mutations in CUL7, OBSL1 and CCDC8 in 3-M syndrome lead to disordered growth factor signalling.

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P E Clayton Research Topics

Disease

2Growth Disorders
10/2019 - 01/2002
2Hypopituitarism (Sheehan's Syndrome)
08/2015 - 10/2008
2Miller-McKusick-Malvaux-Syndrome (3M Syndrome)
01/2013 - 12/2012
2Delayed Puberty
04/2011 - 04/2008
2Pituitary Dwarfism
08/2009 - 10/2008
2Adrenal Insufficiency (Adrenal Gland Hypofunction)
09/2008 - 10/2001
2Precocious Puberty
01/2007 - 11/2003
2Weight Gain
11/2003 - 10/2001
1Type 1 Diabetes Mellitus (Autoimmune Diabetes)
05/2017
1Pathologic Processes
02/2014
1Congenital Hyperinsulinism
05/2011
1Hypogonadism (Hypergonadotropic Hypogonadism)
04/2011
1Obesity
04/2011
1Hypothyroidism
12/2008
1Muscular Dystrophies (Muscular Dystrophy)
09/2008
1Laron Syndrome (Syndrome, Laron)
02/2007
1Congenital adrenal hyperplasia due to 21 hydroxylase deficiency
01/2005
1Congenital Adrenal Hyperplasia (Hyperplasia, Congenital Adrenal)
01/2005
1Virilism (Virilization)
01/2005
1Body Weight (Weight, Body)
11/2003
1Acromegaly
08/2003
1Crohn Disease (Crohn's Disease)
12/2002
1Wounds and Injuries (Trauma)
07/2002
1Fetal Growth Retardation (Intrauterine Growth Retardation)
01/2002
1Turner Syndrome (Turner's Syndrome)
01/2002
1Neoplasms (Cancer)
08/2001
1Addison Disease (Addison's Disease)
08/2001
1Lipoid congenital adrenal hyperplasia
08/2001
1Pseudotumor Cerebri (Idiopathic Intracranial Hypertension)
12/2000
1Scoliosis
12/2000
1Slipped Capital Femoral Epiphyses
12/2000
1Insulin Resistance
12/2000
1Headache (Headaches)
12/2000
1Chronic Kidney Failure (Chronic Renal Failure)
12/2000
1Type 2 Diabetes Mellitus (MODY)
12/2000
1Familial Glucocorticoid Deficiency 1
10/2000
1Atopic Dermatitis (Atopic Eczema)
04/2000

Drug/Important Bio-Agent (IBA)

6Insulin-Like Growth Factor I (IGF-1)IBA
04/2008 - 10/2000
4LeptinIBA
04/2011 - 07/2002
3Hormones (Hormone)IBA
08/2009 - 11/2003
2Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
08/2015 - 12/2012
2Growth Hormone (Somatotropin)IBA
12/2008 - 01/2002
1Cholecalciferol (Vitamin D3)FDA Link
05/2017
1hydroxide ionIBA
05/2017
1Transcription Factors (Transcription Factor)IBA
02/2014
1Proteins (Proteins, Gene)FDA Link
02/2014
1Insulin-Like Growth Factor II (Somatomedin A)IBA
01/2013
1RNA (Ribonucleic Acid)IBA
01/2013
1Insulin-Like Growth Factor Binding ProteinsIBA
12/2012
1Adenosine Triphosphate (ATP)IBA
05/2011
1KATP ChannelsIBA
05/2011
1Hydrocortisone (Cortisol)FDA LinkGeneric
12/2008
1ProlactinIBA
12/2008
1DystrophinIBA
09/2008
1SaltsIBA
09/2008
1acid labile subunit insulin-like growth factor binding proteinIBA
04/2008
1Goserelin (Zoladex)FDA Link
01/2007
16-chloro-2-(1-piperazinyl)pyrazine (CPP)IBA
01/2007
1Gonadotropin-Releasing Hormone (GnRH)FDA Link
01/2007
1FludrocortisoneIBA
01/2005
1Steroid 21-Hydroxylase (21 Hydroxylase)IBA
01/2005
117-alpha-Hydroxyprogesterone (17 Hydroxyprogesterone)IBA
01/2005
1Insulin-Like Growth Factor Binding Protein 3IBA
11/2003
1Insulin-Like Growth Factor Binding Protein 1IBA
11/2003
1GhrelinIBA
11/2003
1pegvisomantFDA LinkGeneric
08/2003
1Somatostatin (Somatotropin Release-Inhibiting Factor)IBA
08/2003
1Leptin ReceptorsIBA
08/2003
1Glutamine (L-Glutamine)FDA Link
12/2002
1Adrenal Cortex Hormones (Corticosteroids)IBA
10/2001
1steroidogenic acute regulatory proteinIBA
08/2001
1LipidsIBA
08/2001
1Glucose (Dextrose)FDA LinkGeneric
12/2000
1Corticotropin Receptors (ACTH Receptor)IBA
10/2000
1Adrenocorticotropic Hormone (ACTH)FDA Link
10/2000
1Melanocortin Receptors (Melanocortin Receptor)IBA
10/2000
1GlucocorticoidsIBA
04/2000

Therapy/Procedure

4Therapeutics
10/2019 - 12/2000
1Nutritional Support (Artificial Feeding)
12/2002